Lavender (Lavander officianlis) has peer reviewed research describing a decrease in blood brain barrier permeability in rats, 100-200mg per kg per day IP (1). It provides neuroprotection, antioxidant, anti-inflammatory and anti-anxiety benefit. It may be helpful in mild pain and depression. Oral doses using alcohol tinctures or oil infusions were preferred over topical application or inhalation of essential oil. The oral mechanism is believed to be the GABA receptors. (2) Lavender has been shown to reduce pain and and increase healing when applied topically to apthous ulcers. There may be a synergy with cannabis. CBD also provides beneficial actions through GABA receptors. (3)
Doses ranged from 80-600 mg per kg per day. I do not have personal experience with oral lavender. I assume the weight measurement is dry lavender using organic lavender with an olive or hemp seed oil infusion or GRAS essential oil. There are widely accepted techniques for tinctures and infusions, although the mathematics to estimate doses will require additional effort. The best approach will be to start low and go slow as with cannabis.
- Neuroprotective effect of pretreatment with Lavendula officianalis ethanolic extract on on blood brain permeabil ity in a rat stroke model, Zahra Rabini etal. Asian Pacific Journal of tropical medicine. Sept2014, 421-426
- Lavender and the Nervous System. Peir Hussein etal. Evidence Based Complimentary and Alternat Med. 2013
- Cannabinoid Regulation of Fear and Anxiety an Update. Elani P. Papgianna etal. Curr Psychiatry Rep. 2018: 21(6):38
James Brent DDS